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São Paulo Research Foundation (FAPESP)
Post-doctoral Fellowship in Osteoimmunology
São Paulo Research Foundation (FAPESP)
FAPESP funded by taxpayers in the state of São Paulo, with the mission to support research projects in institutions of higher education and research in all fields of knowledge.
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Published: 7 days ago
Application deadline: Jan 18
Location: São Paulo/SP, Brazil
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Post-doctoral Fellowship in Osteoimmunology

Nº: 2566

Field of knowledge: Dentistry

FAPESP process: 2015/24637-3

Project title: MSCs and M2 as determinants of the constructive or destructive nature of inflammatory microenvironments associated with bone tissue

Working area: Osteoimmunology – Dentistry

Number of places: 1

Start: 2019-03-01

Principal investigator: Gustavo Pompermaier Garlet

Unit/Instituition: Faculdade de Odontologia de Bauru, Universidade de Sao Paulo

Deadline for submissions: 2019-01-18

Publishing date: 2018-12-06

Locale: Al. Octávio Pinheiro Brisola, 9-75, Bauru

E-mail for proposal submission: garletgp@usp.br

Summary

The Department of Biological Sciences of Bauru School of Dentistry University of São Paulo (FOB/USP), offers a post-doctoral opportunity within the project "MSCs and M2 as determinants of the constructive or destructive nature of inflammatory microenvironments associated with bone tissue". The works will be conducted in the Laboratory of Osteoimmunology, under the supervision of Prof. Dr. Gustavo Pompermaier Garlet. 

The project aims to elucidate the role of macrophage polarization in tissue repair and to biomaterials implantation, and its impact in the subsequent osseointegration processes. Specifically, the project focus in the experimental study of the effects of intracellular signaling elements modulation described as essential for macrophage polarization to M1/M2 phenotypes in bone repair, osseointegration and biomaterials grafting models. 

The post-doctoral researcher will be responsible for in vivo and in vitro assays (see specific skills description in sequence), to be developed in a multidisciplinary group, in a collaborative research environment, using available equipments of the unit and shared facilities, and activities in partnership with a collaborating institution overseas. 

Requirements 

- The candidates must present training that involves the areas of Histology, Bone Biology and Immunology, preferably in the Osteoimmunology field, proven by the history of graduate activities and publications;
- Have completed the doctorate for a maximum of two years (until the deadline for application);
- Motivation to productively work in an interdisciplinary environment;
- Fluency in English. The project involves direct collaboration with a partner institution abroad, thus being an essential ready to the candidate for the full execution of the project;
- Experience in the development of experimental models in mice, including animal handling skills, experience in experimental surgery and knowledge of experimental therapeutic pathways;
- Experience in techniques of histopathological analysis, histomorphometry, immunohistochemistry, immunofluorescence, computerized microtomography, birefringence, cell culture (macrophages, osteoblasts and osteoclasts), flow cytometry, ELISA, RealTimePCR and PCRarray. 

Applications 

The interested should send a message to Prof. Dr. Gustavo Pompermaier Garlet (lead researcher of the thematic project) via the e-mail garletgp@usp.br, identified with the subject: PD FELLOWSHIP OSTEOIMMUNOLOGY FOB/USP, until the 18/01/2019 (deadline for applications). 

The documents should be sent in PDF format (all sent in a single e-mail): 

- A letter describing your achievements in research and detailing how your training contemplates the desired profile;
- Curriculum Vitae with academic experience (foreigners). Brazilian applicants must follow the specific guidelines for this call described in the FAPESP website (http://www.fapesp.br/en/5100);
- Two (2) letters of recommendation. 

Selection 

The selection will be made based on the candidates CV, focused on the experience in the research of the project area and the publications tracking, as well in the letters of presentation and recommendation, being all the listed documents compulsory for the confirmation of the candidates’ application. Candidates may be asked for an interview throughout the selection process. 

This opportunity is open to candidates of all nationalities. The selected candidate will receive a FAPESP postdoctoral fellowship, in the amount of BRL 7.373,10 per month, and a research contingency fund (technical reserve), equivalent to 15% of the annual value of the scholarship and which must be spent on items directly related to research activities. 

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